COMPARISON OF VARIOUS CORRELATION ON IRMA FOR CA19-9 AND CA50 IN THE DIGESTIVE SYSTEM TUMOUR

This paper compared various correlation of IMRA for CA19-9 and CA50 in the digestive system tumour antigen, such as linearity, sensitivity, analytical range, precision as well as storage and stability and so on. And it also determined serum level of CA19- 9 and CA50 of patients with different tumours. The results showed it was well correlated to CA19- 9 and CA50 as a marker of digestive system tumour. Particularly high levels of both markers were found in patients with pancreastic colonic cancer. Therefore it is possible to obtain a higher sensitivity and acceptable specificity by combination with CA19-9 and CA50.     

Identification of Apolipoprotein C-I as a Potential Wilms’ Tumor Marker after Excluding Inflammatory Factors

Wilms’ tumor is one of the most common malignant tumors observed in children, and its early diagnosis is important for late-stage treatment and prognosis. We previously screened and identified protein markers for Wilms’ tumor; however, these markers lacked specificity, and some were associated with inflammation. In the current study, serum samples from children with Wilms’ tumors were compared with those of healthy controls and patients with systemic inflammatory response syndrome (SIRS). After exclusion of factors associated with inflammation, specific protein markers for Wilms’ tumors were identified. After comparing the protein peak values obtained from all three groups, a protein with a m/z of 6438 Da was specified. Purification and identification of the target protein using high-pressure liquid chromatography (HPLC) and two-dimensional liquid chromatography-linearion trap mass spectrometry(2D-LC-LTQ-MS) mass spectrometry, respectively, revealed that it was apolipoprotein C-I (APO C-I). Thus, APO C-I is a specific protein marker for Wilms’ tumor.     

次同步谐振下机组轴系弯扭振动信号分析

分析了次同步谐振下机电扭振互作用的原因.针对现场难以实现的困难,提出并设计了汽轮发电机组模拟系统的次同步谐振试验,并将HHT应用到次同步谐振下的机组弯扭振动的信号分析.Hilbert谱图定量刻画了次同步谐振下轴系弯扭振动的快速发展过程,直观准确地表现了弯扭信号的本质特征.分析表明,次同步谐振下轴系的弯振和扭振是相互影响、相互作用的,发现扭振有抑制轴系复杂频率振动的能力.当次同步谐振的扭振发生时,扭振含有的丰富频率成分发生了变化,并且弯振的二倍频消失.     

饱和-非饱和非稳定渗流作用下岩质边坡稳定性分析

对岩质边坡在水位下降时坡体内的饱和—非饱和非稳定渗流和坡体稳定性进行了分析,渗流分析采用有限元法,坡体稳定分析采用有限元强度折减法。以塑性区位移突变作为边坡失稳判据,此时折减系数值即为坡体安全系数。以十里铺水库为例,对库岸岩体边坡进行了分析,并得出在水库水位降落影响下边坡的稳定安全系数随降落时间的增长而增大的结论。     

Comparative analysis of a large panel of non-starch polysaccharides reveals structures with selective regulatory properties in dendritic cells

Scope: Structural‐based recognition of foreign molecules is essential for activation of dendritic cells (DCs) that play a key role in regulation of gut mucosal immunity. Orally ingested non‐starch polysaccharides (NSP) are ascribed many health‐promoting properties, but currently we lack insight into the impact of structure and size for their capacity to affect immune responses. Methods and results: This study addresses the importance of chemical structure, size, origin and presence of contaminants for the capacity of both dietary and non‐food NSP to modulate DC. Of 28 NSP products, β‐glucans of microbial and plant origin and the galactomannan guar gum were found to modulate the DC cytokine pattern induced by the Toll‐like receptor 4‐ligand LPS giving rise to reduced IL‐12p70 and increased IL‐10 levels, whereas IL‐6 production was unaffected. A large proportion of the tested NSP were able to down‐regulate LPS‐induced IL‐12p70 production. The most potent NSP induced up‐regulation of CD86 on DC independently of LPS stimulation. Cereal‐based β‐glucans showed less potency than β‐glucans of microbial origin, but proper molecular weight composition and preparation may improve effectiveness. Conclusions: Collectively, this comparative study revealed that some plant‐derived NSP besides those of microbial origin exert modulation of the DC phenotype, with the exact structure being important for the activity.     

摇摆状态一维相控阵天线波束指向修正

由于载机平台摇摆,一维相控阵天线姿态会发生倾斜,从而影响波束指向.为此,提出了一种修正方法,给出了适应于各种监视雷达系统(如二次航管系统)工作原理的详细修正流程及算法.试验结果表明,所提方法使天线能维持高指向精度.     

Crack Tip Opening Angle Measurement Methods and Crack Tunnelling in 2024‐T351 Aluminium Alloy

Abstract: The crack tip opening angle (CTOA) fracture criterion is one of the most promising fracture criterion used to characterise the stable tearing process in metallic materials. Traditional methods used for the experimental characterisation of the CTOA involve accurate identification of the crack tip at each tearing event. Recently alternative methods have been proposed that reduce the necessity of accurately defining the current crack and rely more on the shape of the crack flanks to define the CTOA. In addition, these methods define an ‘apparent crack tip’, which may be different from the actual surface crack tip and may provide insight into the amount of crack‐front tunnelling that is occurring. In the current research, compact tension specimens fabricated from 6.35 mm thick 2024‐T351 aluminium alloy plate were evaluated to investigate different CTOA measurement methods and their potential for estimating crack‐front tunnelling. In addition to characterizing the CTOA, fatigue marker bands were employed to map the evolution of crack‐front tunnelling. The experimental critical CTOA values obtained from the alternative methods were noticeably lower than that obtained from the traditional approach and showed noticeably more scatter. When compared to the experimentally obtained marker bands, the alternative methods indicated limited potential for predicting crack‐front tunnelling.     

一种陆基二次雷达监测站布站仿真测算方法

二次监视雷达是航空交通管制的重要设备,只有保护二次雷达信号不受干扰,才能保证飞行安全。文中简要介绍了二次雷达的主要功能,提出了陆基二次雷达监测站布站的一种仿真测算方法,给出了计算公式和计算条件。然后,通过设置地面二次雷达、机载二次雷达、陆基无线电监测站的技术参数,给出了陆基二次雷达监测站的仿真布站结果。     

基于双目视觉的医疗机器人摆位系统测量方法

为了实现精确放疗过程中精确定位和肿瘤位置的精确测量,建立了基于双目视觉的医疗机器人摆位测量系统,并对系统所采用的摄像机标定方法、标记点识别及其三维坐标计算、摆位系统的位置验证等算法进行研究。建立基于双目视觉的医疗机器人摆位测量系统;提出了一种对摄像机采用基于平面棋盘格和立体标定模板相结合的摄像机标定新方法;采用Roberts梯度算子对图像分割的方法,识别标记点中心并计算其三维坐标;通过比较基于双目视觉计算和三维坐标测量仪器测量的各个标记点三维坐标的摆位误差,实现放疗过程中位置验证和精确摆位。实验结果表明:摄像机的标定精度为36.5×10-3 mm和各个标记点的三维坐标平均偏差为δX=0.573mm、δY=0.495mm、δZ=0.430mm,测量方法可获得较高的标定精度和摆位精度,能满足精确放疗对高精度摆位系统的临床需求。